Gastroenterology
HER-2 positivity is a high risk of recurrence of stage I gastric cancer
Seonhoo Kim, Yeon-Ji Kim, Woo Chul Chung
Korean J Intern Med. 2021;36(6):1327-1337. Published online August 26, 2021
Background/Aims: The treatment of gastric cancer remains unsatisfactory. We aimed to investigate the prognostic value of immunohistochemical staining in gastric cancer.
Methods: We analyzed 505 (279 early staged, 226 advanced-staged) gastric cancer tissues from patients who underwent radical gastri..
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Optimizing glucose control for diabetic patients undergoing percutaneous coronary intervention
Haseong Chang, Sung-Hea Kim
Korean J Intern Med. 2021;36(6):1320-1322. Published online November 1, 2021
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Eosinophilic endotype of chronic obstructive pulmonary disease: similarities and differences from asthma
Andrew Li, Hiang Ping Chan, Phyllis X.L. Gan, Mei Fong Liew, W.S. Fred Wong, Hui-Fang Lim
Korean J Intern Med. 2021;36(6):1305-1319. Published online October 12, 2021
Approximately 25% to 40% of patients with chronic obstructive pulmonary disease (COPD) have the eosinophilic endotype. It is important to identify this group accurately because they are more symptomatic and are at increased risk for exacerbations and accelerated decline in forced expiratory volume i..
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Recent advances in airway imaging using micro-computed tomography and computed tomography for chronic obstructive pulmonary disease
Naoya Tanabe, Toyohiro Hirai
Korean J Intern Med. 2021;36(6):1294-1304. Published online October 6, 2021
Chronic obstructive pulmonary disease (COPD) is a complex lung disease characterized by a combination of airway disease and emphysema. Emphysema is classified as centrilobular emphysema (CLE), paraseptal emphysema (PSE), or panlobular emphysema (PLE), and airway disease extends from the respiratory,..
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Role of asymptomatic hyperuricemia in the progression of chronic kidney disease and cardiovascular disease
Yousuf Waheed, Fan Yang, Dong Sun
Korean J Intern Med. 2021;36(6):1281-1293. Published online July 8, 2021
Previous research has investigated whether hyperuricemia serves as an independent risk factor for cardiovascular and renal diseases. Hyperuricemia is defined as an abnormally high level of uric acid (UA; i.e., serum urate level > 6.8 mg/dL). Hyperuricemia has been considered a complication of chroni..
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Hepatic sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic cell transplantation: historical and current considerations in Korea
Jae-Ho Yoon, Chul Won Choi, Jong-Ho Won
Korean J Intern Med. 2021;36(6):1261-1280. Published online September 24, 2021
Hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is a rare but severe complication of hematopoietic cell transplantation (HCT) showing high mortality. Multiple risk factors for SOS/VOD were identified, but it is often confused with other hepatic complications due to nonspecif..
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Effect of omalizumab as add-on therapy to Quality of Life Questionnaire for Korean Asthmatics (KAQLQ) in Korean patients with severe persistent allergic asthma
Jae-Woo Jung, Hae-Sim Park, Choon-Sik Park, Sang-Heon Cho, Inseon S. Choi, Hee-Bom Moon, Soon Seog Kwon, Ho Joo Yoon, Jung Won Park, Jong-Myung Lee, Dong-Chull Choi, Byoung Whui Choi
Korean J Intern Med. 2021;36(5):1260 Published online September 1, 2021
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Distinctive arterial collaterals caused by aortic occlusion in a patient with antiphospholipid syndrome
Shunya Kaneshita, Masei Suda, Masato Okada
Korean J Intern Med. 2021;36(5):1258-1259. Published online June 17, 2020
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A mass-like lesion encasing the aortic arch and descending aorta: immunoglobulin G4-related periaortitis
Chewan Lim, Chul-Min Ahn, Hyun-Chel Joo, Jung Yoon Pyo, Young-Guk Ko
Korean J Intern Med. 2021;36(5):1256-1257. Published online October 15, 2020
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Geriatrics
Validity of the Clinical Frailty Scale in Korean older patients at a geriatric clinic
Hee-Won Jung, Il-Young Jang, Ji Yeon Back, Seunghyun Park, Chan MI Park, Seung Jun Han, Eunju Lee
Korean J Intern Med. 2021;36(5):1242-1250. Published online December 30, 2020
Background/Aims: We aimed to assess the validity of the Korean translated version of the Clinical Frailty Scale (CFS) in determining the frailty status in geriatric outpatients.
Methods: The records of 123 ambulatory outpatients who had undergone CFS and comprehensive geriatric assessments (CGAs) i..
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Hospital Medicine
Clinical Frailty Scale, K-FRAIL questionnaire, and clinical outcomes in an acute hospitalist unit in Korea
Seung Jun Han, Hee-Won Jung, Jae Hyun Lee, Jin Lim, Sung do Moon, Sock-Won Yoon, Hongran Moon, Seo-Young Lee, Hyeanji Kim, Sae-Rim Lee, Il-Young Jang
Korean J Intern Med. 2021;36(5):1233-1241. Published online June 4, 2021
Background/Aims: Frailty increases the risks of in-hospital adverse events such as delirium, falls, and functional decline in older adults. We assessed the feasibility and clinical relevance of frailty status in Korean older inpatients using the Clinical Frailty Scale (CFS) and Korean version of the..
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Rheumatology
Evaluation of body composition using computed tomography in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
Sung Soo Ahn, Byung-Woo Yoo, Hyeok Chan Kwon, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
Korean J Intern Med. 2021;36(5):1221-1232. Published online August 18, 2020
Background/Aims: Measures of body composition, including visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and skeletal muscle area (SMA), are considered important prognostic factors in chronic diseases. The association of these measures with auto-inflammatory disorders, such as anti..
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The usefulness of trabecular bone score in patients with ankylosing spondylitis
Seoung Wan Nam, Yoon-Kyoung Sung, Dam Kim, Soo-Kyung Cho, Yoonah Song, Yun Young Choi, Yongjin Sim, Tae-Hwan Kim
Korean J Intern Med. 2021;36(5):1211-1220. Published online June 30, 2020
Backgrounds/Aims: This study was performed to reveal the usefulness of the trabecular bone score (TBS) in assessing bone strength in patients with ankylosing spondylitis (AS) in comparison with dual-energy X-ray absorptiometry (DXA) methods.
Methods: A total of 215 AS patients (75.8% male) were enr..
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Infectious diseases
Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro
Sung Im Choi, Mee Soo Chang, Taeeun Kim, Kyung Hwa Chung, Seongman Bae, Sung-Han Kim, Chan Jin Yoon, Young Kyoon Kim, Jun Hee Woo
Korean J Intern Med. 2021;36(5):1204-1210. Published online August 18, 2021
Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in a hospital setting in Korea.
Methods: This study was conducted i..
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Hemato-oncology
Thrombotic and hemorrhagic events in 2016 World Health Organization-defined Philadelphia-negative myeloproliferative neoplasm
Ik-Chan Song, Sang Hoon Yeon, Myung-Won Lee, Hyewon Ryu, Hyo-Jin Lee, Hwan-Jung Yun, Seon Young Kim, Deog-Yeon Jo
Korean J Intern Med. 2021;36(5):1190-1203. Published online July 22, 2021
Background/Aims: Recent changes in the diagnostic criteria for myeloproliferative neoplasms (MPNs) and increasing patient numbers necessitate updating of the data on vascular events in patients with such disorders.
Methods: In this single-center study, thrombotic and hemorrhagic events were retrosp..
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Risk factors for neutropenic fever in non-Hodgkin’s lymphoma patients with primary granulocyte colony-stimulating factor prophylaxis
Yu Ri Kim, Soo-Jeong Kim, Yong Park, Sung Yong Oh, Hwan-Jung Yun, Yeung-Chul Mun, Jin Seok Kim; the Korean Society of Hematology Lymphoma Working Party
Korean J Intern Med. 2021;36(5):1181-1189. Published online July 16, 2021
Background/Aims: Febrile neutropenia (FN) interferes with the proper chemotherapy dose density or intensity in non-Hodgkin’s lymphoma (NHL) patients. Chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) ± rituximab has an intermediate FN risk. Prophylactic granulocy..
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Nephrology
Reduction in proteinuria after immunosuppressive therapy and long-term kidney outcomes in patients with immunoglobulin A nephropathy
Shin Chan Kang, Hyung Woo Kim, Tae Ik Chang, Ea Wha Kang, Beom Jin Lim, Jung Tak Park, Tae-Hyun Yoo, Hyeon Joo Jeong, Shin-Wook Kang, Seung Hyeok Han
Korean J Intern Med. 2021;36(5):1169-1180. Published online February 10, 2021
Background/Aims: Despite controversy regarding the benefits of immunosuppressive therapy in immunoglobulin A nephropathy (IgAN), clinical outcomes may vary depending on the patient’s responsiveness to this therapy. This study evaluated long-term kidney outcomes according to the extent of proteinur..
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